pentobarbital will minimize the extent or influence of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Sturdy or average CYP3A4 inducers might boost price of diazepam elimination; therefore, efficacy of diazepam can be lessened.pentobarbital will reduce the extent or effect of estrogens esterified by i